To delete an existing application profile in the Custom Application Profile window, follow these steps:
The name of the application profile disappears from the listbox immediately when you click Delete. However, the profile is not actually deleted until you click OK to close the Custom Application Profile window.
If, after you click Delete, you decide that you do not want to delete the profile, then click Cancel to close the Custom Application Profile window.
Click here to read about deleting the two sample profiles, OVNote and ISPF.