WebSphere Application Server Version 6.0.x is interoperable with other WebSphere Application Server versions under certain conditions.
WebSphere Application Server Version 6.0.x is generally interoperable with WebSphere Application Server Versions 5.0.x and 5.1.x. You should apply the latest fix level to support interoperability. Currently, there are no interim fixes necessary to support interoperability. In order to interoperate between WebSphere Application Server for z/OS and a WebSphere Application Server product on a non-z/OS machine, however, you must take the following steps: