To utilize TCP/IP port reservations refresh support, your port and port range configuration statements must reside in a separate file. No other TCP/IP configuration statements can be in this file. This file must be pointed to, with an INCLUDE statement, from the PROFILE.TCPIP in your existing configuration.
If your port configurations are in a separate file, then select Yes and msys for Setup will be able to provide the refresh function.
If your port configurations are not in a separate file, then select No. However, msys for Setup will not be able to collect the refresh data.